imipenem + cilastine
J - Antiinfectives For Systemic Use -> J01 - Antibacterials For Systemic Use -> J01D - Other Beta-Lactam Antibacterials -> J01DH - Carbapenems -> J01DH51 - Imipenem And Enzyme Inhibitor
Administration category:
Free
Medicine group:
antibacterial
Brand name:
Tienam
Safety margins
| Weight | ROA | Dosage | |
|---|---|---|---|
|
ROA: iv |
Dosage: min. 250mg 4 dd to max. 1000mg 4 dd |
||
|
Comments:
dosisadvies heeft betrekking op imipenem component |
|||
Kidney function
| ROA | GFR | Dosage | Interval | Comments |
|---|---|---|---|---|
| ROA: iv | ||||
|
GFR: 10 - 30 |
Dosage: 50% |
|||
Renal elimination:
70%
Dosage:
dependent on kidney function
Renal function-replacement therapy
CAPD: 500 mg elke 12 uur, max. 1000 mg per dag
Hemo dialysis: 500 mg elke 12 uur, max. 1000 mg per dag, op dialysedagen 1 dosis na de dialyse
CAV / VVHD: 500 mg elke 12 uur, max. 1000 mg per dag
Pregnancy
Due to the expiration of the alphanumeric classification for use in pregnancy and lactation, reference is made to the current, online information of the Teratology Information Service (TIS) of LAREB:
- http://www.lareb.nl//Teratologie/Naslagwerk-GZB/GZB---Zwangerschap#TOC_Middelen_bij6
- http://www.lareb.nl//Teratologie/Naslagwerk-GZB/GZB---Borstvoeding#TOC_Middelen_bij16
For individual advice, consult an expert on site.
Metadata
Swab vid: M-1495.4
Updated: 06/16/2019 - 20:05
Status: Published