Home Therapy Heart and thorax
Home Therapy Heart and thorax

endocarditis - streptokokken. MIC >0.12–<0.5 µg/mL

Advices

≥ 18 years
Priority Medication Remarks
Medication:

benzylpenicilline iv 24million. IU/24h 4 weeks

+

gentamicine iv 3mg/kg 1dd 2 weeks
Remarks:

natieve klep

opladen met benzylpenicilline 2 miljoen EH IV
Medication:

benzylpenicilline iv 24million. IU/24h 6 weeks

+

gentamicine iv 3mg/kg 1dd 6 weeks
Remarks:

kunstklep

opladen met benzylpenicilline 2 miljoen EH IV
≥ 18 years

Indications: Penicillineallergie
Priority Medication Remarks
Medication:

ceftriaxon iv 2000mg 1dd 4 weeks
Remarks:

natieve klep
Medication:

ceftriaxon iv 2000mg 1dd 6 weeks

+

gentamicine iv 3mg/kg 1dd 6 weeks
Remarks:

kunstklep
≥ 18 years

Indications: beta-lactam anafylaxie
Priority Medication Remarks
Medication:

vancomycine iv continuous per 24 hours 4 to 6 weeks
Remarks:

natieve klep 4 weken - kunstklep 6 weken

General comments

vancomycine dosering: vancomycine dosering continu.pdf

Bij BMI > 30 gentamicine op Adjusted Body Weight (ABW) doseren

Salvage therapy (voor alledrie de schema's): alleen na 2 weken IV behandeling:

  • linezolid 2x600mg po + rifampicine 2x600mg po OF
  • moxifloxacine 1x400mg po + rifampicine 2x600mg po OF
  • moxifloxacine 1x400mg po + clindamycine 3x600mg po

Sources

Antimicrobial resources

The following antimicrobial agents have been used in these recommendations:

External antimicrobial resources
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Metadata

Swab vid: G-395205.8
Updated: 10/12/2022 - 22:11
Status: Published