endocarditis - s aureus (MSSA)
Advices
| Priority | Medication | Remarks |
|---|---|---|
|
Medication: flucloxacilline iv 12g continuous per 24 hours 6 weeks |
Remarks:
natieve klep |
|
|
Medication: flucloxacilline iv 12g continuous per 24 hours 2 weeks |
Remarks:
natieve klep, ongecompliceerd rechtszijdig (zie onder) |
|
|
Medication: flucloxacilline iv 12g continuous per 24 hours 6 weeks +
rifampicine po 450mg 2dd 6 weeks +
gentamicine iv 3mg/kg 1dd 2 weeks |
Remarks:
kunstklep |
|
|
Medication: linezolid po 600mg 2dd +
rifampicine po 600mg 2dd |
Remarks:
salvage therapy, na ten minste 2 weken IV behandeling. |
Sources
-
IDSA guidelines infective endocarditis - 2015 ESC guideline infective endocarditis - 2015
-
POET trial NEJM 2019.pdf
POET trial NEJM 2019. orale uitbehandeling endocarditis
-
POET trial NEJM 2019 - appendix.pdf
POET trial NEJM 2019. orale uitbehandeling endocarditis - appendix met AB schema's
Antimicrobial resources
The following antimicrobial agents have been used in these recommendations:
External antimicrobial resources
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Metadata
Swab vid: G-395265.4
Updated: 08/19/2022 - 15:43
Status: Published
General comments
2 weken behandeling ALLEEN voor rechtszijdige endocarditis zonder cardiale of extra-cardiale complicaties.
voeg rifampicine pas toe na 3-5 dagen adequate antibiotische behandeling.
Gentamicine: Bij BMI > 30 doseren op Adjusted Body Weight (ABW): www.globalrph.com/ibw_calc.cgi